Your time is limited, so don’t waste it living someone else’s life. Don’t be trapped by dogma – which is living with the results of other people’s thinking. Don’t let the noise of others’ opinions drown out your own inner voice. And most important, have the courage to follow your heart and intuition. They somehow already know what you truly want to become. Everything else is secondary.
>> In France, after the new coronavirus was confirmed on January 24, 2020, a lot of harassment and discrimination against Asians occurred . It is aimed at Asians such as Chinese, Korean, Japanese, Vietnamese, Filipino , and taxis and trains that refuse to board Chinese, Korean, Japanese have appeared   ].
In the ranking of the number of infected people in the world, the United States is alone, with 1.34 million people, accounting for more than a quarter of the total infected people of 402 million people as of May 10.
I think that the trilingual diplomacy of Britain has created the situation in the Middle East, where terrorism is frequent nowadays, and has repeatedly carried out wrongdoing by repeatedly discriminating against blacks, Indians, and yellow races.
Bologna - From social media comes good news about the Coronavirus, perhaps decisive, which has scientific foundations and is disseminated by an authoritative doctor from Rizzoli of Bologna, Sandro Giannini. His is a highly qualified curriculum: Full Professor of Orthopedics and Traumatology and of Physical Medicine at the University of Bologna since 1989, director of Clinic I at the Rizzoli Orthopedic Institute and of the Gait Analysis Laboratory, partner in European projects and in national and international research programs, author of more than 600 presentations at national and international conferences and more than 400 articles in Science Citation Index journals. His message gives great hope. Let's read:
“I don't want to seem overwhelming to you, but I think I've demonstrated the cause of coronavirus lethality. Only at Blessed Matthew are there 2 cardiologists who turn over 150 beds to do echocardium with enormous effort and one is me. Terrible fatigue! However, of what some supposed, but could not be sure, we now have the first data. People go to resuscitation for generalized venous thromboembolism, especially pulmonary. If this were the case, resuscitations and intubations are of no use because first of all you have to dissolve, indeed prevent these thromboembolisms. If you ventilate a lung where blood does not reach, it is not needed! In fact 9 out of 10 die. Because the problem is cardiovascular, not respiratory! It is venous microthrombosis, not pneumonia that determines fatality!
And why are thrombi formed? Because inflammation, as per school text, induces thrombosis through a complex but well-known pathophysiological mechanism. Then? Contrary to what scientific literature, especially Chinese, said until mid-March, it was that anti-inflammatories should not be used. Now in Italy anti-inflammatories and antibiotics are used (as in the influences) and the number of inpatients collapses. Many deaths, even 40 years old, had a history of high fever for 10-15 days that was not treated properly. Here inflammation has destroyed everything and prepared the ground for thrombi formation. Because the main problem is not the virus, but the immune reaction that destroys the cells where the virus enters. In fact, our COVID departments have never entered patients with rheumatoid arthritis! Because they make cortisone, a powerful anti-inflammatory!
Therefore, hospitalizations in Italy are decreasing and it is becoming a disease that is treated at home. By taking care of it well at home, you avoid not only hospitalization, but also the thrombotic risk. It was not easy to understand it because the signs of microembolism have faded, even at the echocardium. But this weekend I compared the data of the first 50 patients between those who breathe badly and those who don't and the situation appeared very clear. For me you can go back to playing and reopen the business. Quarantine street. Not now. But time to publish this data. Vaccine can arrive calmly. In America and other states that follow the scientific literature that calls for NOT to use anti-inflammatories is a disaster! Worse than in Italy. And they are old and cheap drugs. " (Associated Medias - Red / Giut)
Bologna – Dai social arriva una buona notizia sul Coronavirus, forse risolutiva, che ha fondamenta scientifiche ed è diffusa da un medico autorevole del Rizzoli di Bologna, Sandro Giannini. Il suo è un curriculum molto qualificato: Professore ordinario di Ortopedia e Traumatologia e di Medicina Fisica presso l’Università di Bologna dal 1989, direttore della Clinica I presso l’Istituto Ortopedico Rizzoli e del Laboratorio di Gait Analysis, partner in progetti europei e in programmi di ricerca nazionali e internazionali, autore di più di 600 presentazioni a congressi nazionali ed internazionali e più di 400 articoli in riviste Science Citation Index. Il suo messaggio dà grande speranza. Leggiamolo:
“Non vorrei sembrarvi eccessivo ma credo di aver dimostrato la causa della letalità del coronavirus. Solo al Beato Matteo ci sono 2 cardiologi che girano su 150 letti a fare ecocardio con enorme fatica e uno sono io. Fatica terribile! Però, di quello che alcuni supponevano, ma non ne riuscivano a essere sicuri, ora abbiamo i primi dati. La gente va in rianimazione per tromboembolia venosa generalizzata, soprattutto polmonare. Se così fosse, non servono a niente le rianimazioni e le intubazioni perché innanzitutto devi sciogliere, anzi prevenire queste tromboembolie. Se ventili un polmone dove il sangue non arriva, non serve! Infatti muoiono 9 su 10. Perche il problema è cardiovascolare, non respiratorio! Sono le microtrombosi venose, non la polmonite a determinare la fatalità!
E perché si formano trombi? Perche l’infiammazione come da testo scolastico, induce trombosi attraverso un meccanismo fisiopatologico complesso ma ben noto. Allora? Contrariamente a quello che la letteratura scientifica, soprattutto cinese, diceva fino a metà marzo era che non bisognava usare antinfiammatori. Ora in Italia si usano antinfiammatori e antibiotici (come nelle influenze) e il numero dei ricoverati crolla. Molti morti, anche di 40 anni, avevano una storia di febbre alta per 10-15 giorni non curata adeguatamente. Qui l’infiammazione ha distrutto tutto e preparato il terreno alla formazione dei trombi. Perche il problema principale non è il virus, ma la reazione immunitaria che distrugge le cellule dove il virus entra. Infatti nei nostri reparti COVID non sono mai entrati malati di artrite reumatoide! Perche fanno il cortisone, un potente antinfiammatorio!
Pertanto, in Italia ospedalizzazioni si riducono e sta diventando una malattia che si cura a casa. Curandola bene a casa eviti non solo ospedalizzazione, ma anche il rischio trombotico. Non era facile capirlo perché i segni della microembolia sono sfumati, anche all’ecocardio. Ma questo week end ho confrontato i dati dei primi 50 pazienti tra chi respira male e chi no e la situazione è apparsa molto chiara. Per me si può tornare a giocare e riaprire l’attività commerciali. Via quarantena. Non subito. Ma il tempo di pubblicare questi dati. Vaccino può arrivare con calma. In America e altri stati che seguono la letteratura scientifica che invita a NON usare antinfiammatori e’ un disastro! Peggio che in Italia. E sono farmaci vecchi e che costano pochi euro.”
12 Dr. Hiroshi Nishiura is one of the few professionals of mathematical models of infectious diseases in Japan, and it is well known that his ability is outstanding. However, many people don't understand mathematical models themselves (I must confess that I can't say that I understand all of the findings because I'm not a professional of mathematical models either), so his findings and comments are easily deified. Because the contents of the mathematical model are a complete black box to many people, it makes it seem like the oracle is coming out like a shrine's oracle. Much of Japan's infection control policy relies on the Nishiura theory. So there is nothing wrong with that, but one of the problems in Japan is that there is no plan B in case plan A goes bust. Dr. Nishiura is an excellent scholar. It is not God. Hence the need to have that Plan B with the possibility of making a mistake. I am greatly concerned that bureaucrats and politicians who are prone to infallibilism will mistake science for an oracle. It is only when falsifiability is assured that science can continue to be scientific.
Mathematical models are the product of deductive methods. The deductive method is complemented by the inductive or abduction method, which is the basis of scholarship and the common sense of clinical medicine. It's a common occurrence in this industry that no matter how deducibly correct it may seem, it's actually not true. Even a huge intellect like Hegel or Marx can make a mistake by deduction alone.
I'm not saying don't use the model at all. I myself write a paper using a model. However, the model is not infallible, there are assumptions that are assumptions, and the assumptions are often wrong. Making use of Gram's stain means having full knowledge of what Gram's stain cannot do and does not understand, and Gram's stain cannot be used by Gram's stain universalists. It's the same thing. Mathematical models are also utilized in the UK, which is why Brits are very sceptical of their conclusions, and there are always counter-arguments and objections. It is a sound and scientific attitude.
15 Japan's "now" is a well-controlled state of infection, which is much better than Wuhan at its worst, or Italy, Spain, France, England, or New York at the present time. The problem is that it doesn't guarantee that it will "always work".
It is Tokyo that is of concern. The increase in reports of infection is not the only problem. The problem is that more and more infected people are unable to form clusters and cannot be traced. And the number of tests is much lower than that number of positive cases; it's too little that they only tested less than 100 people (the date of testing for the positives is unknown, but it's probably around here) to capture 47 infected people.
Again, it's not necessary to figure out all the infected people. However, it is troubling that the flow of infection, movement and clusters are out of sight. Therefore, the threshold for testing must be lowered in Tokyo. The threshold for testing varies with the circumstances. That's what I explained with the Korean example. Sticking to the Ministry of Health, Labour and Welfare's "standards" will lead to a misunderstanding of the phenomenon itself. Already in the Kansai region, infected people have been found with taste and smell abnormalities, and clusters have been detected from there. I would like to make more use of the athletic sensibilities of these clinicians. I'm not sure "where" in Tokyo is the barrier to lowering the number of inspections, but that barrier needs to be removed immediately.
17 This conceptual diagram that everyone is looking at - lowering the peak of the infection and shifting it to the side. This is all a product of deduction, and I don't know if it's really true. As mentioned above, the UK estimates already suggest that this is not enough. It is possible that the damage that was shifted to the side could simply be "extra-long damage".
And this is the key point: the idea of lowering the peak should not become the notion that the peak must be lowered, or the belief that the peak must be lowered, or the self-implication that the peak is not happening. In a pattern of Japanese failure to stick to Plan A, Diamond Princess allowed no-guard disembarkation by changing "secondary infection should not occur" to "it can't have happened". We need to keep our eyes on reality so that "peak shouldn't happen" doesn't become "I don't want to see a peak. Even if it is an inconvenient truth that we don't want to see.
19 Repeatedly. It's common knowledge in this industry that deductive methods are complemented by inductive methods. Nevertheless, PCR is often false-negative and has little power to determine the status of infection. That's why "testing everything" is so wrong. However, a serum test measuring immunoglobulin IgM and IgG would provide a more accurate picture of the "status of infection in the population. This, however, is not infallible. It is difficult to use for individual cases because it misses early infection, which is why it misses early HIV infection.Whether antibody testing is useful in individual cases remains to be tested, but it is well suited for epidemiological studies on a population basis. Roughly speaking, we can confirm whether the "infection is rampant" in Tokyo right now, or whether it's just an unfounded fear.
As a precedent, serology tests in London showed that the 2009 pandemic flu was 10 times more likely than previously predicted. Antibody testing is often performed after an outbreak, but now is a good time to examine COVID-19, which is becoming a chronic pandemic.
The UK is even more aggressive. The idea is to test for antibodies at home, and if they are found to be infected, they will use it as a basis for self-isolation at home. That strategy is flawed because with the lockdown in place, a negative test does not mean "no self-sequestration". However, the idea is that we want to control the infection as a whole, and I think it is worth considering.
Inductive legal confirmation of how many infections are occurring in Tokyo is necessary and useful. I'm not a prophet, so I don't know what the outcome will be.However, no matter what the outcome, scientists need to accept it and not hesitate to change their thesis and move on to Plan B in some cases. Scientists have to be coherent in their inconsistencies.They may not be coherent in form, but they must be coherent in principles and professionalism. Good faith in the facts.
16 March 2020
If they test positive, isolate them and find out who they have been in close contact with up to 2 days before they developed symptoms, and test those people too. [NOTE: WHO recommends testing contacts of confirmed cases only if they show symptoms of COVID-19]
Washing your hands will help to reduce your risk of infection. But it’s also an act of solidarity because it reduces the risk you will infect others in your community and around the world. Do it for yourself, do it for others.
This afternoon WHO and the International Chamber of Commerce issued a joint call to action to the global business community. The ICC will send regular advice to its network of more than 45 million businesses, to protect their workers, customers and local communities, and to support the production and distribution of essential supplies.
Like me, I’m sure you have been touched by the videos of people applauding health workers from their balconies, or the stories of people offering to do grocery shopping for older people in their community.
This amazing spirit of human solidarity must become even more infectious than the virus itself. Although we may have to be physically apart from each other for a while, we can come together in ways we never have before.
英語版 文字起こし (自動生成）のコピペを、英語として読める文章にした。いくつか聞き取れていないところがあるので、わかる人がいたらトラバで教えてほしい。聞き取れていないところは「(inaudible01)」みたいに番号をふって記載してあるので、
I was very concerned of the number of the people who got infected with the COVID-19 disease infections. Then I was wondering why this is[sic](was)*2 happening. I wanted to enter into the cruise ship and wanted to be useful in helping to containing infection there.
I spoke with several people and finally one officer at working for Ministry of Health and Labor called me yesterday, saying that well you can come and enter into a cruise ship and do the infection control works.
On the way to go to Yokohama I got another call from the same officer, saying, "Somebody didn't like me. So you can't get into the cruise ship." He was not able to say who, and he was not able to say why, but certainly some power over him affected his decision and I was blocked from entering into the ship.
Then after several discussions he found another way that if you could come as a DMAT member, you can come into the the cruise ship. DMAT is the disaster management medical team in Japan and usually deals with a disaster not infectious diseases, but because of the lack of the people who could help people inside a cruise ship to get out of the ship, or the managing of people, and so on, DMAT was requested to enter into the cruise ship.
Additionally, I got another call that some people didn't like me getting into the cruise ship present even as a DMAT member. So another discussion happened then the I waited about one hour in Shin Yokohama Station, and finally the officer find a way. [He said] that "If you work for DMAT not as an infection prevention specialist but as an ordinary routine DMAT officer working under (inaudible01) DMAT doctor doing a routine job, then you could come into the cruise ship."
I entered the ship. Then I found the chief officer of the DMAT and spoke with him. I said, "Well I was assigned to the DMAT members (inaudible02) out whatever you want to say." Then he said, "Well, you don't have to work DMAT work because that's not your specialty. You are an infection prevention specialist, so why don't you do the infection control." Then I said, "Fine, I spoke with the superior of him who is[sic](was) in charge of the all the DMAT operations, and he also said, "You are an infection control person, so you should do infection control." I said, "Fine." But he said, "Well, you shouldn't be here as a DMAT member. You should come as (inaudible03) infection control specialist." He was not very happy about that while I was inside the DMAT. But because that was not my decision, there was no other way. So I said, "Well I have to do it."
So the people could come and go, (inaudible04) a PPE, off PPE. Crews were just walking around, the officers of the Ministry Health and Labor were walking around, DMAT people were walking around, psychiatrists were walking around.
Anyways I (have) dealt with a lots of infections (for) more than twenty years. I was in Africa dealing with the Ebola outbreak. I was in another country dealing with the cholera outbreak. I was in China in 2003 to deal with the SARS, and I saw many febrile patients there. I never had fear of getting infection myself for Ebola, SARS, (and) cholera, because I know[sic](knew) how to protect myself and how to protect others, and how the infection control should be. So I could do the adequate infection control; protect myself, and protect others.
But inside (the) Princess Diamond, I was so scared. I was so scared of getting COVID-19 because there was no way to tell where the virus is. No Green Zone, no Red Zone. Everywhere could have the virus and everybody was not careful about it.
I spoke with the head officer of the Ministry of Health and Labor and he was very unhappy with my suggestion of protecting DMAT people and other staffs so that no other secondary transmission would occur.
Then after several hours of talking to people and finding problems, I found a lot of issues there. For example, informed consent of getting a PCR from the people in the ship whereas(? inaudible05) on a paper, and that paper was going back and forth, back and forth with the room of the infection from the paper, by touching there[sic](it). So I suggested that maybe it's better to abandon the paper-type informed consent but rather getting the informed consent verbally would be more protective, and so on and so on.
I think I was reasonable. I never yell at anybody, I never criticize anybody personally, but I was trying to be constructive that we try to seek the constructive but immediate improvement to protect everybody inside the ship.
Then about five o'clock, the person from the quarantine office came in and approaced. (He) said, "Well you have to be out because you'll not be allowed inside the ship." Because I was inside the ship as a temporary officer of the quarantine. Apparently my bank(? inaudible06) was removed by somebody, and nobody said who, and then I was out.
The officer who offered me the job of infection control said he was sorry. Then I asked him, "So what do you wanna do? Do you want to infect everybody in the ship? It will be thousands of people who could potentially get COVID-19.
I don't criticize DMAT people. They were infection control specialists. Society of Infection Prevention entered, a lot of specialists came in, but they spent only a few days and they left. And they said they were fearful of getting infections themwelves.
I'll be out of my medical services at Kobe University Hospital for maybe next two weeks to avoid further infections to occur. That is very likely to occur if you keep zero infection control inside the ship, the Diamond Princess, like this.
You might know that there is no CDC*3 in Japan, but I thought there must be some specialists called on and was[sic](were) in charge of infection control in ship. It's not expecting[sic](expected) (that) nobody was a professional infection control specialist, and (that) only the bureaucrats were doing the jobs, completely layman's work, violatiing all the infection control principles and risking people inside (of*4) further infections, so I'm not very surprised to see many new positive PCR to be broadcasted every day.
Hundreds of people got infected and a lot of people from outside Japan decided to take the people away from the ship and bring them to their home countries by airplane and offered them another 14 days of quarantine. I hope this will be an opportunity to raise a question (about) what is happening inside the ship.
I wish all the international bodies to request Japan to change. I wish everybody to call for the protection of people inside the Diamond Princess. Otherwise there'll be far more infections for passengers, for crews, for DMAT members, for psychiatrists, for officer(s) of the Ministry of Health and Labor. DMAT members consist of nurses and doctors and that they will go back to the hospital they work routinely and they might infect their patients further to spread the disease. I can't bear with it. I can't bear with it.
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My few interactions with Jeffrey Epstein came at the request of Joi Ito, for the purposes of fundraising for the MIT Media Lab. Prior to these interactions, I was told by Joi that Epstein had cleared the MIT vetting process, which was the basis for my participation. My last interaction with Epstein was in 2015. Still, by agreeing to participate in any fundraising activity where Epstein was present, I helped to repair his reputation and perpetuate injustice. For this, I am deeply regretful.
In an e-mail to the Globe sent after the meeting, Negroponte said he told Ito that “he should” take Epstein’s contribution, and “I would say that again based on what we knew at the time. . . . “Epstein is an extreme case. But then do you take Koch money? Do you take Huawei money? And on and on?” Negroponte said.
I had known of Joi’s contact with Epstein since about the beginning. He had reached out to me to discuss it. We are friends (Joi and I), and he knew I would be upset by his working with a pedophile.
Joi believed that he did not. He believed Epstein was terrified after the prosecution in 2011. He believed he had come to recognize that he would lose everything. He believed that whatever else he was, he was brilliant enough to understand the devastation to him of losing everything. He believed that he was a criminal who had stopped his crime. And nothing in his experience with Epstein contradicted this belief.
エプスタインはもう虐待者ではないと Joi は信じていた。エプスタインは2011年に起訴された後、恐怖に襲われている、と伊藤穣一は信じていた。エプスタインはすべてを失うことになるのを認識するに至ったと伊藤穣一は信じていた。いずれにせよ、エプスタインはすべてを失うという絶望を理解する十分な知性があると、伊藤穣一は信じていた。エプスタインはもう犯罪を犯さない犯罪者だと、伊藤穣一は信じていた。伊藤穣一はエプスタインに会って、その信念に矛盾することを何も感じなかった。
IF you are going to take type 3 money, then you should only take it anonymously. . . . Good for them, for here, too, transparency would be evil.
Sure, it wasn’t blood money, and sure, because anonymous, the gift wasn’t used to burnish Epstein’s reputation.
I know that Farrow’s article is crafted to draw the following sentence into doubt: Everything Joi did in accepting Epstein’s money he did with MIT’s approval. I trust the MIT review will confirm it (yes, I remain exactly that naive). So why is he resigning, rather than others in the administration?
And if Ito must go because Epstein’s wealth was accepted anonymously, who else should go because of blood money accepted openly? Will the planet have an equal advocate who demands justice for the Koch money? Or the victims of opioid abuse for the Sackler money?
So put the parts together: The MediaLab accepted an anonymous contribution from Epstein through the help and direction of Joi. The Lab did not (as “Professor Anonymous” wrote to me, his outrage apparently blinding him to irony) “help reputation-launder a convicted sex offender.” It would have, had it not be anonymous; but that’s the point about it being anonymous.
Peter Cohen, a former director of development and strategy, said in a statement that when he joined the Media Lab in 2014, it already had established procedures for handling Epstein’s contributions. Cohen said he understood that those policies were “authorized by and implemented with the full knowledge of MIT central administration.”
Second, it is now clear that senior members of the administration were aware of gifts the Media Lab received between 2013 and 2017 from Jeffrey Epstein’s foundations. Goodwin Procter has found that in 2013, when members of my senior team learned that the Media Lab had received the first of the Epstein gifts, they reached out to speak with Joi Ito. He asked for permission to retain this initial gift, and members of my senior team allowed it. They knew in general terms about Epstein’s history – that he had been convicted and had served a sentence and that Joi believed that he had stopped his criminal behavior. They accepted Joi’s assessment of the situation. Of course they did not know what we all know about Epstein now.
Joi sought the gifts for general research purposes, such as supporting lab scientists and buying equipment. Because the members of my team involved believed it was important that Epstein not use gifts to MIT for publicity or to enhance his own reputation, they asked Joi to agree to make clear to Epstein that he could not put his name on them publicly. These guidelines were provided to and apparently followed by the Media Lab.
Information shared with us last night also indicates that Epstein gifts were discussed at at least one of MIT’s regular senior team meetings, and I was present.
I am aware that we could and should have asked more questions about Jeffrey Epstein and about his interactions with Joi. We did not see through the limited facts we had, and we did not take time to understand the gravity of Epstein’s offenses or the harm to his young victims. I take responsibility for those errors.