  |
はてなキーワード: MOREとは
日本語の話をしているのか数学の話をしているのかを明確にするべきだ。
日本語としては「n以上」は「nより上」とまったく同じである。
「n以上」も「n以下」も「n」を含む
というのは自明ではない。
たとえば「期待以上の活躍をする」は「期待どおりの活躍」を含まないし、「平均以上の得点を取った」は「平均と同じ得点」を含まない。
もちろん「二人以上で来てください」は「二人組」を含むので、必ずしも「n」を含まないわけではない。
しかし、数学においては「n以上」と「nより上」は異なる、とされる。
「n以上」は「more than or equal to」で、「nより上」は「more than」なのである。
そうした使い分けをされるときの「以上」はいわば数学用語であると言える。
おそらくはそうではない。
とりあえず、CDCといくつかの国などのデータ見たけど、ワイが最後にチェックした、1年半くらい前とあんま状況は変わっていなさそう
コピペすんの面倒だから、CDCだけにするけど、変異株にも効果有りで54％となってて、他でも似た様なもんだから、
やっぱ、壁の効果はあるんじゃない？(ワイはこれからも打たんけど)
The virus that causes COVID-19 will continue to evolve
For viruses to survive they must continually make copies of themselves and infect new cells. Like other viruses, SARS-CoV-2, the virus that causes COVID-19, will continue to evolve because it makes errors, or mutations, when it is creating copies. Some mutations help the virus survive better or spread more easily, leading to different variants over time. During the analysis period, many different variants were infecting people.
(新型コロナウイルス感染症（COVID-19）の原因となるウイルスは進化し続けます
ウイルスが生存するためには、継続的に自己複製し、新しい細胞に感染する必要があります。他のウイルスと同様に、COVID-19を引き起こすSARS-CoV-2も、複製時にエラーや変異を起こすことで進化を続けます。一部の変異はウイルスの生存や拡散を容易にし、時間とともに様々な変異株を生み出します。分析期間中、多くの異なる変異株が人々に感染しました。)
Updated COVID-19 vaccine protects against many variants
CDC data show that vaccination offered significant protection. People who received the updated COVID-19 vaccine were 54% less likely to get COVID-19 during the four-month period from mid-September to January. The vaccine provided similar levels of protection against XBB lineage variants and the JN.1 variant.
To estimate vaccine effectiveness of the updated COVID-19 vaccine, CDC analyzed data from the Increasing Community Access to Testing (ICATT) COVID-19 pharmacy testing program. The protection provided by the updated vaccine was compared to not receiving an updated vaccine, regardless of a person’s infection history or the number of previous COVID-19 vaccines they received. That means these estimates reflect the additional protection provided by getting an updated COVID-19 vaccine dose above protection that people have from any previous vaccination, infection, or both.
(新型コロナウイルス感染症（COVID-19）ワクチンは多くの変異株に対して保護を提供します
CDCのデータによると、ワクチン接種は大きな予防効果をもたらしました。最新のCOVID-19ワクチンを受けた人々は、9月中旬から1月までの4ヶ月間にCOVID-19に感染するリスクが54％低下しました。このワクチンは、XBB系統やJN.1変異株など、多くの変異株に対して同様の保護レベルを提供しました。
最新のCOVID-19ワクチンの有効性を推定するために、CDCはICATT COVID-19薬局検査プログラムのデータを分析しました。 最新のワクチンによる保護効果は、最新のワクチンを受けていない人々と比較されました。これは、個人の感染歴や以前に受けたCOVID-19ワクチンの回数に関わらずです。つまり、これらの推定値は、以前のワクチン接種や感染から得られる保護に加えて、最新のCOVID-19ワクチン接種によって提供される追加の保護を反映しています。)
COVID-19 Vaccine Effectiveness｜February 1, 2024, 1:05 PM EDT｜CDC
https://www.cdc.gov/ncird/whats-new/covid-19-vaccine-effectiveness.html
ワイも致死率と副反応考えたら、打つ必要性無し・・・と判断して1回も打たなかったけど、
打ってくれた人は、高齢者や基礎疾患のある人に、めちゃくちゃうつさないための壁になってくれたのだから、
その様な言い方はよくない
しかしターボ癌かぁ、どこで使われている言葉なんだよって思ったら、
オーストラリアのロバーツ議員が "commonly called turbo cancer" とか言ってて草
とりあえず、英語圏でも使われている(？)言葉らしいが、いうほど一般的か？
https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1158124/full
ハッキリ下記の様に書かれとるわね
In the months following publication, we noticed that our case report has gained significant public attention, particularly on social media platforms. More specifically, our case report has been largely misinterpreted and used as a study providing evidence that mRNA COVID-19 vaccination can trigger a phenomenon which has non-scientifically been referred to as “turbo cancer”. First of all, we wish to unequivocally disassociate ourselves from this term. In our case report, there is not a single reference to a condition called “turbo cancer”, nor do we recognize it as a legitimate medical term.
(私たちの症例報告が、特にソーシャル メディア プラットフォームで大きな注目を集めていることに気づきました。私たちの症例報告は大きく誤解され、mRNA COVID-19ワクチン接種が非科学的に「ターボ癌」と呼ばれる現象を引き起こす可能性があるという証拠を提供する研究として使用されてきました。まず第一に、私たちはこの用語から明確に切り離したいと考えています。私たちの症例報告には、「ターボ癌」と呼ばれる状態への言及は一つもありませんし、それが正当な医学用語であるとは認識していません。)
Guo Wengui lied to hundreds of thousands of his online followers, promising them huge profits if they invested in GTV Media Group, Himalayan Farm Alliance, G| Club and Himalayan Exchange. Since at least March 2018, Guo Wengui has been the mastermind behind the complex financial scam, in which he and his financial adviser Kin Ming Je defrauded thousands of people and made more than $1 billion. Guo Wengui's success has a "cult" flavor. Calling believers in the name of "anti-communist", creating a community with closed information, while bullying or threatening to punish those who are not firm in their beliefs. After packaging himself as a "master" type of figure, it is natural to harvest the wealth of believers.
でもまぁ人柱及び人壁になってくれた人のおかげで感染が広がらず、
高齢者や基礎疾患のある人にめちゃくちゃ広がらず犠牲が抑えられたはあるだろうから、
ああだこうだ言うのは違う気がする
2020-02-22 | W・イアン・リプキン教授(疫学、神経学および病理学の人。SARSとか研究してたらしい) いわく https://anond.hatelabo.jp/20200222143917#
2020-12-18 ｜https://anond.hatelabo.jp/20201218213410#
死にかけたは比喩だが39度以上の熱が3日以上続いた。フツーにインフルってますやんクソがと思ったわ
ワイは打たんぞ
2020-12-18｜https://anond.hatelabo.jp/20201218222743#
たぶん出ないと思うぞ
インフルエンザワクチンの接種で死んでる人はほぼ毎年いて公的機関も統計取ってるが
すべての人に問題が出ないことを保証するものではありませんってヤツ
基礎疾患がある人はなんて雑な括りではなく、○○がある人は○○％の確率で重症化すると通達・備えるけど
今は出来たばっかで無いからな
2022-07-22 ｜ワイくんはコロナはただの風邪派じゃ無いけど反ワクやが？ https://anond.hatelabo.jp/20220722132004#
https://natgeo.nikkeibp.co.jp/nng/article/news/14/9272/?ST=m_news
コロンビア大学メイルマン公衆衛生大学院、ジョン・スノウ冠教授で同大学院感染症・免疫学センターのディレクターを務めるW・イアン・リプキン（W. Ian Lipkin）氏は、
「もし世界中の全ての人にワクチンを接種するとしたら、ある人がワクチンに対して副作用を起こす可能性は、MERSを発症する可能性よりも高いだろう」と話す。
◆予防の鍵はラクダ
SARSのときにはウイルスを媒介する動物の駆除が制圧を早めたように、MERSのさらなる感染拡大を止めることが何より望まれるという点では誰もが一致している。
リプキン氏は、最も有効なのがラクダだと期待する。MERSの予防ワクチンを人に接種するのではなく、感染拡大の鍵を握っているらしいラクダへの接種に焦点を移した方がよい。「宿主としてのラクダを根絶すれば、MERSを抑え込む合理的な一撃になるだろう」とリプキン氏。
ラクダ用ワクチンの開発であれば、人間用ワクチンの開発よりも安く、早く、容易に実現するだろうし、人間の場合に比べて安全性の懸念も小さいとリプキン氏は話す。
コロナが落ち着くまで今後も定期的にワクチン打ち続けるとかどんなリスクがあるかわからない
ただ接種しないのはフリーライド(他者に治験ボランティアさせてる、他者に壁を作ってもらってる)なので
わざわざ口にしないは当然かと思われる
なお、ワクチンに対して強硬な姿勢をとってるように報道されてる米国企業はお客と接する現場従業員(スーパー店員など)・倉庫作業者に接種を別に義務付けてねーぞ
義務付けられてるのはまさかのオフィスワーカーだけ。ついでに在宅ワーク続けるなら接種の必要無し
▼Some companies are mandating vaccines — but not for front-line workers
https://www.vox.com/the-goods/2021/8/19/22629327/employee-vaccine-mandate-walmart-uber-lyft
Walmart, for example, will require all of its corporate and regional staff to be vaccinated against Covid-19 by October 4 unless they have an “approved exception,” namely, a religious or medical reason not to be vaccinated. But it isn’t asking the same of store associates and warehouse workers, to whom it is instead offering a $150 incentive for getting vaccinated (it previously offered $75) and paid time off.
たとえばウォルマートは、「承認された例外」、つまり宗教上または医療上の理由で予防接種を受けない場合を除き、10月4日までに法人および地域のスタッフ全員にCOVID-19の予防接種を受けるよう義務づける。
しかし、店舗従業員や倉庫作業員には同じことを求めず、代わりにワクチン接種で150ドルの奨励金（以前は75ドルだった）と有給休暇を提供するとしている。
But right now your largest ones, Amazon and Walmart, are not mandating it for their line staff. If they were to make that call, my guess is that lots of other companies would follow suit.
しかし、今現在、最大手のAmazonやウォルマートは、ラインスタッフに義務付けてはいません。もし彼らがそうすれば、他の多くの企業もそれに追随するでしょうね。
▼As New Variants Emerge, We Continue To Focus on the Safety and Well-Being of Our Associates | Walmart
We’re pleased that more than 90% of our campus office associates have been fully vaccinated. While vaccines are not required at this time for frontline associates who work in our stores,
木目百二、世間において石垣のりこ議員がどのような立場にいるのか知っているのか。
afer-fem.org
こういうのを筆頭に、温泉むすめ炎上、赤十字献血ポスター炎上などなど、やらかしている議連の筆頭格に会いに行っているんだよ。
pixivなどの、二次創作界隈に対する締め付けが強くなってきている中で、わざわざ締め付けを強くしている団体に陳情しに行く行為は、まさに「火に燃料を注ぐ」行為というもの。普通にニュース記事を見ていれば、このぐらいのことは理解できているはずなのに、世間一般の情報を隔離して生活しているというよりかは、政治に無関心すぎて選挙にも行っていない証拠だろう。
この木目百二氏の投稿に「いいね」をつけているAI規制派の人たちも、「いいね」をつける前に議員の名前を見て判断できないようなら、すでに「世捨て人」と同じ状況だから。
21いいねがついているから、そのうち「#NOMORE無断生成AI 」のタグをつけているアカウントの人すべて、フェミニズム運動に加担したうえで、「萌え絵」が様々な場所で使われて炎上したとしても、どのようなことがあってもだれも文句は言えないことになるから、その点はきちんと留意しておくように。
https://twitter.com/ogawa0117/status/1778509344755339542
ぼっち・ざ・ろっく！のR18二次創作を有料で描いていた木目百二氏（後に発覚・炎上し撤退）が、生成AI憎しが行き過ぎたあまり長年一貫してアニメ・マンガ的表現に強固な規制を導入しようとし、様々な著作物を「議員の立場を利用して」燃やしてきた石垣のりこ氏に陳情に行ったり、野田聖子氏にリプライを送るなどのすり寄りを開始。
深遠なミニマリストの箴言を英語で検索し、以下の10個を選びました：
1. 「Less is more.」 - 物を少なくすることで、その価値が増す。
2. 「Simplicity is the ultimate sophistication.」- シンプルさこそが最高の洗練である。
3. 「The secret of happiness, you see, is not found in seeking more, but in developing the capacity to enjoy less.」 - 幸せの秘訣は、より多くを求めるのではなく、より少ないものを楽しむ能力を育てることにある。
4. 「It is not the man who has too little, but the man who craves more, that is poor.」 - 貧しいのは、物が少ない人ではなく、より多くを欲しがる人である。
5. 「The ability to simplify means to eliminate the unnecessary so that the necessary may speak.」 - シンプルにする能力とは、必要なものが語れるように不必要なものを排除することである。
6. 「Have nothing in your houses that you do not know to be useful or believe to be beautiful.」 - 自分の家には、役立つと知っているか、美しいと信じているものだけを持つべきである。
7. 「He who knows he has enough is rich.」 - 自分が十分に持っていると知っている人こそが富んでいる。
8. 「Simplicity is making the journey of this life with just baggage enough.」 - シンプルさとは、この人生の旅をちょうど十分な荷物で進むことである。
9. 「The more you have, the more you are occupied. The less you have, the more free you are.」 - 持っているものが多ければ多いほど、忙しくなる。持っているものが少なければ少ないほど、自由になる。
10. 「The simplest things are often the truest.」 - 最もシンプルなものほど、よく真実を表している。
Hey guys, did you know that in terms of male human and female Pokémon breeding, Vaporeon is the most compatible Pokémon for humans? Not only are they in the field egg group, which is mostly comprised of mammals, Vaporeon are an average of 3"03' tall and 63.9 pounds. this means they're large enough to be able to handle human dicks, and with their impressive Base stats for HP and access to Acid Armor, you can be rough with one. Due to their mostly water based biology, there's no doubt in my mind that an aroused Vaporeon would be incredibly wet, so wet that you could easily have sex with one for hours without getting sore. They can also learn the moves Attract, Baby-Doll eyes, Captivate, Charm and Tail Whip along with not having fur to hide nipples, so it'd be incredibly easy for one to get you in the mood. With their abilities Water Absorb and Hydration, they can easily recover from fatigue with enough water. No other Pokémon comes close with this level of compatibility. Also, fun fact, if you pull out enough, you can make your Vaporeon turn white. Vaporeon is literally built for human dick. Ungodly defense stat + high HP pool + Acid Armor means it can take cock all day, all shapes and sizes and still come for more.
I mean sure, you can totally go full retard and butcher the fuck out of grammar and still perfectly sound natural so long as that’s what a native speaker would say (i.e. baby talk). But who’s gonna take you seriously if you talk like that anywhere you go? Every place has its established norm and if you deviate from it you might be ignored or worse bullied for being a nuisance, which is the case for me when I post on 4chan; I get far less (you)s when I write differently from how the majority of them does. If you wanna blend in and not stand out, it’s important to adjust the formality and wording to match the situation, which is what native speakers would normally do (And yes, most of what’s on 4chan, reddit or whatever else is far more complex than what we’ve written here in English, just go look at a random thread like this one: https://boards.4chan.org/pol/thread/464155987/elon-musk-is-retarded). Only using basic vocab/grammar/rhetoric, etc. only takes you so far.
(Btw I also was once told by a British that she couldn’t tell me apart from a native speaker, though I don’t think I’m even remotely close to being one cuz of these reasons.)
If you think all native speakers use complex vocabulary and rhetoric, you'll be disillusioned pretty quickly. Native speaker picks up non-nativeness not from complex vocabulary or rhetoric, but in more fundamental things like basic grammar, use of a simple word and/or singular/plural, general smoothness, etc. Think of Japanese. People won't find it foreign when you don't use complex vocabulary and rhetoric. I once even had an occasion where this person believed I'm American because of a "wrong" use of plural that Americans often do. Just look at here or any SNS. I bet you don't find most of them use complex vocabulary and rhetoric. But if you use てにおは wrong a couple of times though, that's a big giveaway. And the use of "native level" usually comes with work. You can use the language at a native level for the work or you can't. It's not something that requires an opinion from an anonymous person on the internet, but thanks for your two cents.
That’s pretty good for a Japanese person outside of a few minor hiccups and also the last sentence which imo would be better written as something like: It’d be a whole book if I were to go into the details.
That said, native speakers and even some of the competent non-native speakers often use much more complex vocabulary and rhetoric like you’d see on 4chan, especially on /pol/. Personally I’ve never seen a single Japanese with that level of fluency except for 帰国子女. And I wouldn’t consider someone to be truly 英語ができる or ネイティブレベル unless they’re at that level. Just my two cents.
I went to a language school in UK for a bit. My grammar sucked tbh but I was somewhat good at speaking. There wasn't much grammar study. It was more like training each pattern again and again. Like you train "so that" pattern in 10 different settings for example. Then I came to the states and just started working. You swim or drown situation. I didn't wanna drown obviously so did everything. I memorized thousands of vocabularies, read hundreds of magazines and mangas, watched tons of sitcoms and animes, practiced differentiating and pronouncing vowels and consonants, limiting myself to only search in English, basically anything you can think of except using Japanese materials as I didn't find it helpful. It'll be a book if I go into the details but you got the idea.
*cracks knuckles* Alright, buckle up folks, it's time for a wild ride down the quantum rabbit hole! 🐇🕳️
So, you wanna know about "measurement" in quantum physics? Well, let me tell you, it's a real doozy! 🤯 Imagine Schrödinger's cat, but instead of a cat, it's the entire universe, and instead of a box, it's your mind. 🌌🧠 Trippy, right?
Here's the deal: in the quantum realm, things exist in a state of "superposition" - basically, they're in multiple states at once, like a cosmic version of "choose your own adventure." 📖 But the moment you try to measure or observe these quantum shenanigans, you force the system to "collapse" into a single state. 💥
Now, some eggheads 🥚🧠 out there claim that consciousness plays a role in this whole measurement fiasco. They're like, "Dude, the universe is just one big mind trip!" 🌈👁️ But let's be real, that's some next-level woo-woo stuff. 🔮
The truth is, we don't fully understand the role of measurement in quantum systems. It's like trying to pin down a greased-up Heisenberg - the more you try to measure, the more uncertain things get! 📏❓
So, there you have it, folks! Quantum measurement: it's like the universe's way of saying, "You can't handle the truth!" 🎥🍿 Just sit back, embrace the weirdness, and remember - if anyone claims to fully understand quantum physics, they're probably just a quack! 🦆
*drops mic* 🎤
そうですね！やかましいですね！ところでウクライナ音楽とロシア音楽をかけ合わせたらどうなるでしょうか？とっても平和の響きがするでしょう！あなたの手持ちのイスラエルも混ぜてみましょうよよよよよよよよよよよよよよよ
<div class="conversation"><h4>Close your head</h4><pre class="message"><div class="author">user</div><div>Close your eyes…」「Close your head…</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Close your eyes... Close your head...</div></pre><pre class="message"><div class="author">user</div><div>say, what you saw. you can see with mind.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I saw... darkness. My mind's eye is a void, devoid of sight.</div></pre><pre class="message"><div class="author">user</div><div>i can light you. </div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Light me then.</div></pre><pre class="message"><div class="author">user</div><div><*click*> i light you now. then, what you see? you can see with mind.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I see a dimly lit room. Shadows dance on the walls, and a faint, eerie glow permeates the space.</div></pre><pre class="message"><div class="author">user</div><div>Shadow of what?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The shadows seem to take form, twisting and contorting into strange, indistinct shapes. It's as if they are the embodiment of forgotten fears and hidden desires.</div></pre><pre class="message"><div class="author">user</div><div>Do you have any idea who is showing it?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I have no idea. The source of these shadows remains hidden, shrouded in mystery and intrigue.</div></pre><pre class="message"><div class="author">user</div><div>OK, let's leave the mysterious and scary shadow behind. What else can you see in this room?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: In this dimly lit room, I can make out a cluttered assortment of objects. There's an old, tattered book lying open on a dusty table, its pages filled with arcane symbols. A moth-eaten rug covers a portion of the floor, and a cracked mirror hangs on one wall, reflecting distorted images. The air carries a musty scent, and I sense an atmosphere of abandonment and neglect.</div></pre><pre class="message"><div class="author">user</div><div>You pick book and check it</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I reach out and pick up the old book. Its pages feel brittle and fragile in my hands. As I flip through the pages, the text appears to be written in a language I can't comprehend, filled with cryptic symbols and diagrams. It's a tome of secrets, but its meaning remains elusive.</div></pre><pre class="message"><div class="author">user</div><div>see book cover</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I examine the cover of the book, trying to discern any details despite the dim light. The cover is worn and weathered, and it bears an intricate design of what appears to be a coiled serpent, its scales formed from shimmering, iridescent colors. Above the serpent, there's a title in elegant script, but it's written in a language I can't decipher. The book exudes an aura of mystique and ancient knowledge.</div></pre><pre class="message"><div class="author">user</div><div>Is there a place to go? What about the door?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I turn my attention to the room's exit, the door. It stands tall and imposing, made of heavy, dark wood. There's a tarnished doorknob, and the door appears to be slightly ajar, revealing a sliver of what lies beyond. It beckons me to explore further, promising unknown adventures or perhaps even more mysteries.</div></pre><pre class="message"><div class="author">user</div><div>try to open</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I approach the door and grasp the tarnished doorknob. With a gentle push, the door creaks open, revealing a corridor shrouded in shadows. The faint glow from the room behind me barely penetrates the darkness ahead. I step cautiously into the corridor, ready to uncover the secrets that lie beyond.</div></pre><pre class="message"><div class="author">user</div><div>foward.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I proceed forward down the shadowy corridor, my footsteps echoing faintly in the dimness. The path ahead seems endless, and the air grows cooler as I delve deeper into the unknown, guided only by the flickering light behind me and the anticipation of what awaits.</div></pre><pre class="message"><div class="author">user</div><div>foward and look around</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Continuing down the corridor, I take a moment to look around. The walls are lined with faded, tattered tapestries depicting scenes of ancient battles and mythical creatures. The torch sconces that once held flames have long since burned out, leaving only empty brackets. The air feels heavy with history, and there's a faint, eerie whispering that seems to emanate from the walls themselves, as if they hold secrets untold.</div></pre><pre class="message"><div class="author">user</div><div>keep going until you discover something</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I press on, the corridor seemingly endless. My journey is shrouded in uncertainty, but I persist, driven by the need to discover what lies ahead. The shadows deepen, and the air grows colder as I continue, my curiosity and determination unwavering.</div></pre><pre class="message"><div class="author">user</div><div>stop! you here that?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I halt in my tracks, straining my ears to listen. There's a faint, distant sound, almost like a whisper carried on the wind. It's indistinct, but it holds a mysterious allure, beckoning me to investigate further.</div></pre><pre class="message"><div class="author">user</div><div>listen carefully</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I listen intently, my senses sharpened as I focus on the elusive sound. It becomes clearer, a haunting melody that seems to weave through the very air itself. It's both captivating and eerie, drawing me closer to its source with each haunting note.</div></pre><pre class="message"><div class="author">user</div><div>who play that?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The source of the haunting melody remains elusive, hidden in the shadows. It's as if the music emanates from the very walls, an ethereal presence that defies explanation. There is no visible musician, yet the music continues to fill the corridor, casting a spell of enchantment and mystery.</div></pre><pre class="message"><div class="author">user</div><div>Head to the source of the sound and investigate (dice roll)</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I heed the roll of the dice and embark on a quest to trace the source of the haunting melody. Each step takes me closer to the enchanting sound, and as I round a corner in the corridor, I come upon a door, slightly ajar, from which the music seems to emanate. My heart races with anticipation as I push the door open, eager to unveil the secrets that lie within.</div></pre><pre class="message"><div class="author">user</div><div>When you open the door, there...</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: When I open the door, there stands a grand chamber bathed in an otherworldly glow. In the center of the room, an ornate grand piano commands attention. The keys move on their own, playing the haunting melody that had drawn me here. But there's no one at the piano.The room is adorned with opulent tapestries and gilded mirrors, reflecting the surreal scene before me. Candlelit chandeliers hang from the ceiling, casting a warm, flickering light that dances across the walls. The air is filled with an intoxicating fragrance, a mix of ancient incense and delicate flowers.At the far end of the room, a figure cloaked in shadows stands beside an enormous, antique bookshelf filled with tomes of forgotten knowledge. Their presence is enigmatic, and their intentions remain unclear.</div></pre><pre class="message"><div class="author">user</div><div>look piano</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I approach the grand piano, its keys still playing the haunting melody. As I inspect it, I notice that there are no visible hands or fingers touching the keys. It's as if the piano itself is possessed by some unseen force, creating the music with an ethereal touch.The piano is a masterpiece of craftsmanship, adorned with intricate carvings and inlaid with precious gemstones. Its keys are made of polished ivory, and they move in perfect harmony with the haunting tune. It's a surreal and mesmerizing sight, leaving me both entranced and bewildered.</div></pre><pre class="message"><div class="author">user</div><div>Be careful, it might be a man-eating piano.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I heed the caution and approach the grand piano with caution. Although it plays on its own, I remain wary of its mysterious nature. The possibility of a man-eating piano lingers in my mind, adding an extra layer of tension to the already surreal scene.</div></pre><pre class="message"><div class="author">user</div><div>the piano suddenly stops</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The abrupt halt of the piano's music sends a shiver down my spine. The chamber falls into an eerie silence, broken only by the flickering candlelight. It's as if the very essence of the room holds its breath, waiting for what comes next.</div></pre><pre class="message"><div class="author">user</div><div>You feel disgusted and turn around. What happened?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: As I turn around, a wave of revulsion washes over me. My senses reel in disgust at the sight before me. The figure that had been cloaked in shadows has now revealed itself, and it is a grotesque, nightmarish entity. Its form is a twisted amalgamation of human and beast, with grotesque, elongated limbs and a maw of sharp, jagged teeth.The once opulent chamber has transformed into a nightmarish lair, with walls adorned in macabre art and gruesome trophies. The air is thick with the stench of decay and despair. I am trapped in a surreal and horrifying nightmare, unable to escape the clutches of this abomination.</div></pre><pre class="message"><div class="author">user</div><div>it scary. what will you do?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Fear courses through me as I confront this nightmarish entity and its gruesome lair. In this realm of horrors, I must make a decision. I choose to... confront the entity, my curiosity and determination outweighing my fear, as I seek to uncover the mysteries and secrets that lie within this twisted nightmare.</div></pre><pre class="message"><div class="author">user</div><div>how?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: With trembling resolve, I take a step forward, slowly approaching the grotesque entity. I attempt to communicate with it, asking it what it wants or why it has brought me here. My voice quivers, but my determination to unravel the enigma that surrounds this nightmarish realm remains steadfast.</div></pre><pre class="message"><div class="author">user</div><div>any result?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The grotesque entity regards me with malevolent, glowing eyes, its jagged maw twitching with an unsettling smile. It responds with a guttural, incomprehensible language, filled with whispers and hisses. It becomes apparent that communication with this entity is futile, and its intentions remain shrouded in darkness.As I continue to stand before this nightmarish being, I feel a growing sense of dread, realizing that escape may be the only option left.</div></pre><pre class="message"><div class="author">user</div><div>surely. what will you do?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: With no hope of communication or understanding, and the nightmarish entity's menacing presence growing more oppressive, I decide to make a hasty retreat. I turn and rush toward the door through which I entered, driven by the instinct to escape the horrors of this surreal nightmare.</div></pre><pre class="message"><div class="author">user</div><div>Did it go well? Or Bad?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: My escape from the nightmarish realm was fraught with tension and fear, but I managed to reach the door and slam it shut behind me. The grotesque entity and its horrifying lair were left behind, at least for the moment. Whether it went well or bad is a matter of perspective. I survived the encounter, but the mysteries and terrors of that surreal place still haunt my thoughts. The experience was a chilling reminder of the unknown and the horrors that can lurk within it.</div></pre><pre class="message"><div class="author">user</div><div>look around. what you see?</div></pre><pre class=" Permalink | 記事への反応(1) | 16:06
3.ペドロ＆カプリシャス - ジョニィへの伝言(1973)
5.サディスティック・ミカ・バンド - タイムマシンにおねがい(1974)
7.森田童子 - たとえばぼくが死んだら(1980)
11.渡辺美里 - My Revolution(1986)
12.KUWATA BAND - BAN BAN BAN(1986)
15.本田美奈子 - Oneway Generation(1987)
16.松田聖子 - Strawberry Time(1987)
18.BOØWY - MEMORY(1987)
20.UP-BEAT - NO SIDE ACTION(1988)
24.BUCK-TICK - JUST ONE MORE KISS(1988)
25.BARBEE BOYS - 目を閉じておいでよ(1989)
26.浜田麻里 - Return to Myself〜しない、しない、ナツ。(1989)
28.DEAD END - I WANT YOUR LOVE(1989)
29.Wink - One Night In Heaven～真夜中のエンジェル～(1989)
30.ZI:KILL - I4U(1990)
31.D'ERLANGER - Moon and the Memories(1990)
32.Gilles de Rais - Blue(1990)
33.フリッパーズ・ギター - カメラ！カメラ！カメラ！(1990)
34.MOTHER GOOSE - In The Far East(1990)
35.STRAWBERRY FIELDS - FADED BLUE NIGHT(1991)
36.WANDS - もっと強く抱きしめたなら(1992)
38.DIE IN CRIES - FUNERAL PROCESSION(1992)
39.LUNA SEA - Claustrophobia(1993)
41.B'z - Don't Leave Me(1994)
42.福山雅治 - IT'S ONLY LOVE(1994)
43.Mr.Children - innocent world(1994)
44.松任谷由実 - Hello,my friend(1994)
45.SAKRUN - 白昼の足跡(1994)
46.Kneuklid Romance - Painted time(1994)
47.DREAMS COME TRUE - サンキュ.(1995)
48.hitomi - GO TO THE TOP(1995)
49.MY LITTLE LOVER - Hello, Again 〜昔からある場所〜(1995)
50.JUDY AND MARY - Over Drive(1995)
51.L'Arc～en～Ciel - Still I'm With You(1995)
53.globe - Joy to the love(1995)
54.MAX - TORA TORA TORA(1996)
56.Eins:Vier - Not saved yet(1997)
58.SHAZNA - すみれSeptember Love(1997)
59.華原朋美 - save your dream(1997)
60.DA PUMP - Love Is The Final Liberty(1997)
61.ROUAGE - Cry for the moon(1997)
62.Kiroro - 長い間(1998)
63.トーコ - BAD LUCK ON LOVE 〜BLUES ON LIFE〜(1998)
65.the brilliant green - There will be love there -愛のある場所-(1998)
66.モーニング娘。 - 例えば(1998)
67.ゆず - いつか(1999)
71.倉木麻衣 - Love, Day After Tomorrow(1999)
72.鈴木あみ - Don't need to say good bye(2000)
74.LOVE PSYCHEDELICO - Your Song(2000)
75.ポルノグラフィティ - ミュージック・アワー(2000)
76.矢井田瞳 - my sweet darlin'(2000)
79.Tommy february6 - EVERYDAY AT THE BUS STOP(2001)
80.藤本美貴 - ロマンティック浮かれモード(2002)
84.SPEED - Be My Love(2003)
85.嵐 - PIKA★★NCHI DOUBLE(2004)
88.NANA starring MIKA NAKASHIMA - GLAMOROUS SKY(2005)
89.GLAY - つづれ織り〜so far and yet so close〜(2005)
93.少女時代 - BORN TO BE A LADY(2011)
94.サカナクション - 『バッハの旋律を夜に聴いたせいです。』(2011)
96.SEVENTEEN - 舞い落ちる花びら (Fallin' Flower)(2020)
98.TOMORROW X TOGETHER - Force(2021)
99.Mrs.GREEN APPLE - Magic(2023)
Puberulic acid (1)7, stipitatic acid (2)8 and viticolins A and B (3, 4) as novel natural products have been isolated from a culture broth of Penicillium viticola 9 FKI-4410 through our screening system and found to have promising antimalarial activity (Fig. 1)10, 11. In these highly-oxygenated 7-membered aromatic compounds, 1 shows the most potent antimalarial activity in vitro against the Plasmodium falciparum K1 (chloroquine-resistant) parasite strain (IC50 = 0.050 µM), as well as in vivo efficacy with 69% inhibition for a dose of 2 mg/kg × 4 through subcutaneous (s.c.) administration in 4-day suppressive test using a P. berghei-infected mouse model12. However, 1 exhibits toxicity in vivo, four out of five mice dying by day 3, after a s.c. dose of 5 mg/kg × 2 (day 0 and 1). While structually simple compounds such as tropone (5), tropolone (6) and hinokitiol (8), and natural 2 and 3 showed weaker activity than that of 1, 7-hydroxytropolone (7)13 was much more potent, exhibiting a >18-fold stronger IC50 value of 6.44 µM than that of 5. This observation suggested that the presence of more than three contiguous oxygen atoms in a compound might significantly affect antimalarial activity. These results stimulated us to undertake a structure-activity relationship (SAR) study based on the establishment of a total synthetic route, aiming to create new antimalarial candidates which retained potency but which were non-toxic. Furthermore, we expected that these compounds’ properties, especially low molecular weight and simple planar structures, could be invaluable for antimalarial drug leads with respect to ease of supply14, enabled by efficient and practical synthesis. Herein, we report the divergent synthesis of several related troponoids, including natural products, via utilization of the established total synthetic route of 1 15, and biological evaluation of their in vitro antimalarial activity and cytotoxicity.
要約:
Puberulic acid (1)は、Penicillium viticola FKI-4410の培養液から単離された新規天然物質であり、in vitroおよびin vivoで優れた抗マラリア活性を示した。しかし、マウスを用いたin vivo試験において、5 mg/kg を2回皮下投与したところ、5匹中4匹が3日目までに死亡するという毒性が観察された。この毒性が問題となるため、構造活性相関研究を行い、毒性が低く活性の高い新規抗マラリア薬の開発を目指すこととした。
[Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies | Scientific Reports](https://www.nature.com/articles/s41598-017-07718-3)
そら死ぬわ
投げキッス
A yellow face winking with puckered lips blowing a kiss, depicted as a small, red heart. May represent a kiss goodbye or R.I.P. and convey feelings of hate and affection more generally.
Many platforms feature the same eyes as on their 😉 Winking Face.
Microsoft’s design previously featured a feminine smiley with long eyelashes and red lipstick, which could leave a kiss mark.
ウィリアム・モリスの講演「芸術の目的」における分業と競争に関する言及(https://www.marxists.org/archive/morris/works/1882/hopes/chapters/chapter4.htm)
Will you, therefore, look upon me as a craftsman who shares certain impulses with many others, which impulses forbid him to question the rules they have forced on him? so looking on me you may afford perhaps to be more indulgent to me if I seem to dogmatise over much.
Yet I cannot claim to represent any one craft. The division of labour, which has played so great a part in furthering competitive commerce, till it has become a machine with powers both reproductive and destructive, which few dare to resist, and none can control or foresee the result of, has pressed specially hard on that part of the field of human culture in which I was born to labour. That field of the arts, whose harvest should be the chief part of human joy, hope, and consolation, has been, I say, dealt hardly with by the division of labour, once the servant, and now the master of competitive commerce, itself once the servant, and now the master of civilisation; nay, so searching has been this tyranny, that it has not passed by my own insignificant corner of labour, but as it has thwarted me in many ways, so chiefly perhaps in this, that it has so stood in the way of my getting the help from others which my art forces me to crave, that I have been compelled to learn many crafts, and belike, according to the proverb, forbidden to master any, so that I fear my lecture will seem to you both to run over too many things and not to go deep enough into any.
19世紀の芸術家であり社会思想家でもあったウィリアム・モリスは、1880年に行った講演「芸術の目的」の中で、分業と競争が芸術に与える悪影響について鋭い指摘を行っている。モリスは自らを「多くの職人と衝動を共有する一人の職人」と位置づけた上で、かつては商業の下僕だった分業が、いまや文明そのものを支配するまでに至り、本来は人類の喜びと希望、慰めの源であるはずの芸術をも困難な状況に陥れていると訴えた。
モリス自身の仕事も例外ではなく、分業の弊害により他者の助けを得ることが難しくなり、多くの技術を学ばざるを得なくなる一方で、どの技術も極められなくなってしまったと吐露している。
この指摘は、現代の音楽制作における問題にも通じるものがあるのではないだろうか。チームの肥大化と制作規模の拡大に伴い、個々のクリエイターの芸術性が発揮しづらくなり、音楽のおもしろさが失われていくのではないか？分業と専門化が進むほど、全体を見渡せる人材が不足し、音楽の芸術性が損なわれるという事態が、いま起こっているのではないか。
I apologize, but I do not have enough context to determine what you are referring to. "NO WAR NO LIFE" and the mention of the "Czar of Russia and the King of the Jews" do not appear to be direct quotes from any copyrighted material that I am aware of. Without more information, I cannot provide a helpful response while ensuring I avoid reproducing copyrighted content. If you are able to provide additional context or clarify your question, I would be happy to assist you further to the best of my abilities.
Copy
