  |
はてなキーワード: gtとは
興味深く読ませてもらいました。そもそもこんな殴り書きにわざわざ言葉を綴ってくれてありがとうございます。
>一方で現実の戦争体験は反戦平和を訴えるという決まり切った文脈・パッケージでしか語りようがなかった。
こうした語りすら許されていないのが自死遺族だと思っている。だからこそ、
>我々は同じ空間を生きてるようでそれぞれ別の宇宙にいるということだ。
自分と同じ宇宙にいる人が本当に見つからない。自治体主催の当事者の会みたいなのも出たけど、ものすごく心が動いてしんどいから行かなくなった。(あと当事者の会の人間関係も気になるところがあった)
コメントを読んで自分でも返信を書いているうたに気づいたんだけど、自分は配慮してほしいというより、「配慮しろ！」と叫んだり、「被害者がいるんだから配慮したほうが良いのでは？」と知らん人に気にかけてもらえるのが羨ましいんだと思う。
89 名前：🥹英ちゃん😉 (ﾜｯﾁｮｲW 2386-CK/p) 2024/04/03(水) 04:05:45.97 ID:mOsZ+yw90
Ed Piskor committed suicide, people are choosing to believe the claims from people who had it out for him. Molly, girl they claimed he SA'd, tried correcting the claims.
91 名前：🥹英ちゃん😉 (ﾜｯﾁｮｲW 2386-CK/p) 2024/04/03(水) 21:10:04.37 ID:mOsZ+yw90
To "have it out for someone" is to dislike someone to the point of trying to find excuses to fire them, punish them, or cause them trouble/pain.
It is usually said of someone in authority (teacher, boss, cop) or of equal rank (coworker).
"You can't trust her. She really has it out for you, and will twist anything you say to make you look bad in front of the boss.
92 名前：名無しさん＠英語勉強中 (ﾜｯﾁｮｲW 1b12-5W83) 2024/04/03(水) 21:21:30.82 ID:l+Htu6kT0
hàve [(英)have gòt] it ín for A
そのinをoutに変えた感じかもね
>>「毎日パソコンの前に座ってたり、書類の整理をしていたりする人達と違って、皆さんは体力に自身のある人達だと思いますし、そうあらねばいけないという気持ちで働いてください」って訓示があったらこれも炎上するの？
県知事や政治家のような立場の人間がそんなこと言えば当然炎上するだろアホか？
そうですね！やかましいですね！ところでウクライナ音楽とロシア音楽をかけ合わせたらどうなるでしょうか？とっても平和の響きがするでしょう！あなたの手持ちのイスラエルも混ぜてみましょうよよよよよよよよよよよよよよよ
<div class="conversation"><h4>Close your head</h4><pre class="message"><div class="author">user</div><div>Close your eyes…」「Close your head…</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Close your eyes... Close your head...</div></pre><pre class="message"><div class="author">user</div><div>say, what you saw. you can see with mind.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I saw... darkness. My mind's eye is a void, devoid of sight.</div></pre><pre class="message"><div class="author">user</div><div>i can light you. </div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Light me then.</div></pre><pre class="message"><div class="author">user</div><div><*click*> i light you now. then, what you see? you can see with mind.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I see a dimly lit room. Shadows dance on the walls, and a faint, eerie glow permeates the space.</div></pre><pre class="message"><div class="author">user</div><div>Shadow of what?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The shadows seem to take form, twisting and contorting into strange, indistinct shapes. It's as if they are the embodiment of forgotten fears and hidden desires.</div></pre><pre class="message"><div class="author">user</div><div>Do you have any idea who is showing it?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I have no idea. The source of these shadows remains hidden, shrouded in mystery and intrigue.</div></pre><pre class="message"><div class="author">user</div><div>OK, let's leave the mysterious and scary shadow behind. What else can you see in this room?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: In this dimly lit room, I can make out a cluttered assortment of objects. There's an old, tattered book lying open on a dusty table, its pages filled with arcane symbols. A moth-eaten rug covers a portion of the floor, and a cracked mirror hangs on one wall, reflecting distorted images. The air carries a musty scent, and I sense an atmosphere of abandonment and neglect.</div></pre><pre class="message"><div class="author">user</div><div>You pick book and check it</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I reach out and pick up the old book. Its pages feel brittle and fragile in my hands. As I flip through the pages, the text appears to be written in a language I can't comprehend, filled with cryptic symbols and diagrams. It's a tome of secrets, but its meaning remains elusive.</div></pre><pre class="message"><div class="author">user</div><div>see book cover</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I examine the cover of the book, trying to discern any details despite the dim light. The cover is worn and weathered, and it bears an intricate design of what appears to be a coiled serpent, its scales formed from shimmering, iridescent colors. Above the serpent, there's a title in elegant script, but it's written in a language I can't decipher. The book exudes an aura of mystique and ancient knowledge.</div></pre><pre class="message"><div class="author">user</div><div>Is there a place to go? What about the door?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I turn my attention to the room's exit, the door. It stands tall and imposing, made of heavy, dark wood. There's a tarnished doorknob, and the door appears to be slightly ajar, revealing a sliver of what lies beyond. It beckons me to explore further, promising unknown adventures or perhaps even more mysteries.</div></pre><pre class="message"><div class="author">user</div><div>try to open</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I approach the door and grasp the tarnished doorknob. With a gentle push, the door creaks open, revealing a corridor shrouded in shadows. The faint glow from the room behind me barely penetrates the darkness ahead. I step cautiously into the corridor, ready to uncover the secrets that lie beyond.</div></pre><pre class="message"><div class="author">user</div><div>foward.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I proceed forward down the shadowy corridor, my footsteps echoing faintly in the dimness. The path ahead seems endless, and the air grows cooler as I delve deeper into the unknown, guided only by the flickering light behind me and the anticipation of what awaits.</div></pre><pre class="message"><div class="author">user</div><div>foward and look around</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Continuing down the corridor, I take a moment to look around. The walls are lined with faded, tattered tapestries depicting scenes of ancient battles and mythical creatures. The torch sconces that once held flames have long since burned out, leaving only empty brackets. The air feels heavy with history, and there's a faint, eerie whispering that seems to emanate from the walls themselves, as if they hold secrets untold.</div></pre><pre class="message"><div class="author">user</div><div>keep going until you discover something</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I press on, the corridor seemingly endless. My journey is shrouded in uncertainty, but I persist, driven by the need to discover what lies ahead. The shadows deepen, and the air grows colder as I continue, my curiosity and determination unwavering.</div></pre><pre class="message"><div class="author">user</div><div>stop! you here that?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I halt in my tracks, straining my ears to listen. There's a faint, distant sound, almost like a whisper carried on the wind. It's indistinct, but it holds a mysterious allure, beckoning me to investigate further.</div></pre><pre class="message"><div class="author">user</div><div>listen carefully</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I listen intently, my senses sharpened as I focus on the elusive sound. It becomes clearer, a haunting melody that seems to weave through the very air itself. It's both captivating and eerie, drawing me closer to its source with each haunting note.</div></pre><pre class="message"><div class="author">user</div><div>who play that?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The source of the haunting melody remains elusive, hidden in the shadows. It's as if the music emanates from the very walls, an ethereal presence that defies explanation. There is no visible musician, yet the music continues to fill the corridor, casting a spell of enchantment and mystery.</div></pre><pre class="message"><div class="author">user</div><div>Head to the source of the sound and investigate (dice roll)</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I heed the roll of the dice and embark on a quest to trace the source of the haunting melody. Each step takes me closer to the enchanting sound, and as I round a corner in the corridor, I come upon a door, slightly ajar, from which the music seems to emanate. My heart races with anticipation as I push the door open, eager to unveil the secrets that lie within.</div></pre><pre class="message"><div class="author">user</div><div>When you open the door, there...</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: When I open the door, there stands a grand chamber bathed in an otherworldly glow. In the center of the room, an ornate grand piano commands attention. The keys move on their own, playing the haunting melody that had drawn me here. But there's no one at the piano.The room is adorned with opulent tapestries and gilded mirrors, reflecting the surreal scene before me. Candlelit chandeliers hang from the ceiling, casting a warm, flickering light that dances across the walls. The air is filled with an intoxicating fragrance, a mix of ancient incense and delicate flowers.At the far end of the room, a figure cloaked in shadows stands beside an enormous, antique bookshelf filled with tomes of forgotten knowledge. Their presence is enigmatic, and their intentions remain unclear.</div></pre><pre class="message"><div class="author">user</div><div>look piano</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I approach the grand piano, its keys still playing the haunting melody. As I inspect it, I notice that there are no visible hands or fingers touching the keys. It's as if the piano itself is possessed by some unseen force, creating the music with an ethereal touch.The piano is a masterpiece of craftsmanship, adorned with intricate carvings and inlaid with precious gemstones. Its keys are made of polished ivory, and they move in perfect harmony with the haunting tune. It's a surreal and mesmerizing sight, leaving me both entranced and bewildered.</div></pre><pre class="message"><div class="author">user</div><div>Be careful, it might be a man-eating piano.</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: I heed the caution and approach the grand piano with caution. Although it plays on its own, I remain wary of its mysterious nature. The possibility of a man-eating piano lingers in my mind, adding an extra layer of tension to the already surreal scene.</div></pre><pre class="message"><div class="author">user</div><div>the piano suddenly stops</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The abrupt halt of the piano's music sends a shiver down my spine. The chamber falls into an eerie silence, broken only by the flickering candlelight. It's as if the very essence of the room holds its breath, waiting for what comes next.</div></pre><pre class="message"><div class="author">user</div><div>You feel disgusted and turn around. What happened?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: As I turn around, a wave of revulsion washes over me. My senses reel in disgust at the sight before me. The figure that had been cloaked in shadows has now revealed itself, and it is a grotesque, nightmarish entity. Its form is a twisted amalgamation of human and beast, with grotesque, elongated limbs and a maw of sharp, jagged teeth.The once opulent chamber has transformed into a nightmarish lair, with walls adorned in macabre art and gruesome trophies. The air is thick with the stench of decay and despair. I am trapped in a surreal and horrifying nightmare, unable to escape the clutches of this abomination.</div></pre><pre class="message"><div class="author">user</div><div>it scary. what will you do?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: Fear courses through me as I confront this nightmarish entity and its gruesome lair. In this realm of horrors, I must make a decision. I choose to... confront the entity, my curiosity and determination outweighing my fear, as I seek to uncover the mysteries and secrets that lie within this twisted nightmare.</div></pre><pre class="message"><div class="author">user</div><div>how?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: With trembling resolve, I take a step forward, slowly approaching the grotesque entity. I attempt to communicate with it, asking it what it wants or why it has brought me here. My voice quivers, but my determination to unravel the enigma that surrounds this nightmarish realm remains steadfast.</div></pre><pre class="message"><div class="author">user</div><div>any result?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: The grotesque entity regards me with malevolent, glowing eyes, its jagged maw twitching with an unsettling smile. It responds with a guttural, incomprehensible language, filled with whispers and hisses. It becomes apparent that communication with this entity is futile, and its intentions remain shrouded in darkness.As I continue to stand before this nightmarish being, I feel a growing sense of dread, realizing that escape may be the only option left.</div></pre><pre class="message"><div class="author">user</div><div>surely. what will you do?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: With no hope of communication or understanding, and the nightmarish entity's menacing presence growing more oppressive, I decide to make a hasty retreat. I turn and rush toward the door through which I entered, driven by the instinct to escape the horrors of this surreal nightmare.</div></pre><pre class="message"><div class="author">user</div><div>Did it go well? Or Bad?</div></pre><pre class="message"><div class="author">ChatGPT</div><div><rotating_light ALPHABREAKrotating_light>: My escape from the nightmarish realm was fraught with tension and fear, but I managed to reach the door and slam it shut behind me. The grotesque entity and its horrifying lair were left behind, at least for the moment. Whether it went well or bad is a matter of perspective. I survived the encounter, but the mysteries and terrors of that surreal place still haunt my thoughts. The experience was a chilling reminder of the unknown and the horrors that can lurk within it.</div></pre><pre class="message"><div class="author">user</div><div>look around. what you see?</div></pre><pre class=" Permalink | 記事への反応(1) | 16:06
> 自己肯定感は潰される。曖昧ゆえに決まった治療法はなく、すべては自己責任とされてしまう。「おれは発達障害だから人生積んだのだ、何をしても無駄だ」諦念の中
ざっくりいれば、賃金÷平均物価が、ものがどれだけ買えるかを表している。
しかし上げた賃金の回収や、世間的に賃金が上がったならより物が売れるという見込みから、値段設定が見直され、平均の物価はそれ以上に上がるかもしれない。
つまり数列的に表現すれば、賃金0÷平均物価0<賃金1÷平均物価0だが、賃金0÷平均物価0>賃金1÷平均物価1
賃金n÷平均物価nが単調減少、つまり賃金が上がることを望むほど実は豊かでなくなることがありえるのは明らかだろう。
まあ消費する量として豊かでなくなっていっても、物の質がそれ以上の速度に上がれば、「豊かになっている」と感じ続ける状況は起こるかもしれない。
つまり物の質を掛けた、賃金n÷平均物価n×物の質nという値が上がり続けることはありえる。
赤：早稲田大学クイズ研究会4年生中西善哉 緑：立命館大学クイズソサエティー4年生仲田伊織 白：慶應義塾大学クイズ研究会4年生濱口和歩 青：同志社クイズラバーズ2年生吉良拓也
青１３
赤１２ 赤１４ 白１１ 赤 ６ 白 × 青 １ 緑 ８ 白１５
白 ３ 緑 ７ 青１６ 緑１９ 赤 × 青２５ 白１８ 白２４
白 ２ 白２１ 緑２０ 赤２２ 白２３ スルー
緑１７ > １
白 １ 青１０ 緑 ９ 青 ５ 白 ４
+--+--+--+--+--+
| 白 | 白 | 白 | 白 | 青 |
| 白 | 白 | 白 | 白 | 青 |
| 白 | 白 | 緑 | 白 | 青 |
| 白 | 緑 | 緑 | 白 | 青 |
| 白 | 白 | 白 | 白 | 青 |
赤： ０枚 ○ 4 × 1
緑： ３枚 ○ 6 × 0
白： １７枚 ○ 10 × 1
青： ５枚 ○ 6 × 0
Puberulic acid (1)7, stipitatic acid (2)8 and viticolins A and B (3, 4) as novel natural products have been isolated from a culture broth of Penicillium viticola 9 FKI-4410 through our screening system and found to have promising antimalarial activity (Fig. 1)10, 11. In these highly-oxygenated 7-membered aromatic compounds, 1 shows the most potent antimalarial activity in vitro against the Plasmodium falciparum K1 (chloroquine-resistant) parasite strain (IC50 = 0.050 µM), as well as in vivo efficacy with 69% inhibition for a dose of 2 mg/kg × 4 through subcutaneous (s.c.) administration in 4-day suppressive test using a P. berghei-infected mouse model12. However, 1 exhibits toxicity in vivo, four out of five mice dying by day 3, after a s.c. dose of 5 mg/kg × 2 (day 0 and 1). While structually simple compounds such as tropone (5), tropolone (6) and hinokitiol (8), and natural 2 and 3 showed weaker activity than that of 1, 7-hydroxytropolone (7)13 was much more potent, exhibiting a >18-fold stronger IC50 value of 6.44 µM than that of 5. This observation suggested that the presence of more than three contiguous oxygen atoms in a compound might significantly affect antimalarial activity. These results stimulated us to undertake a structure-activity relationship (SAR) study based on the establishment of a total synthetic route, aiming to create new antimalarial candidates which retained potency but which were non-toxic. Furthermore, we expected that these compounds’ properties, especially low molecular weight and simple planar structures, could be invaluable for antimalarial drug leads with respect to ease of supply14, enabled by efficient and practical synthesis. Herein, we report the divergent synthesis of several related troponoids, including natural products, via utilization of the established total synthetic route of 1 15, and biological evaluation of their in vitro antimalarial activity and cytotoxicity.
要約:
Puberulic acid (1)は、Penicillium viticola FKI-4410の培養液から単離された新規天然物質であり、in vitroおよびin vivoで優れた抗マラリア活性を示した。しかし、マウスを用いたin vivo試験において、5 mg/kg を2回皮下投与したところ、5匹中4匹が3日目までに死亡するという毒性が観察された。この毒性が問題となるため、構造活性相関研究を行い、毒性が低く活性の高い新規抗マラリア薬の開発を目指すこととした。
[Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies | Scientific Reports](https://www.nature.com/articles/s41598-017-07718-3)
そら死ぬわ
>なんでそこでいきなり議論が主語ってことになるんだよ。
文脈を追跡すれば想像できる。入試で悪文を出題するのは文脈が読めるかを見るため。
>受験問題で悪文が出るからここで悪文書いていいってことにもならないし。あえて読解力を試すための問題の文章と議論するための文章とでは性質も立場も違うだろ。そんなことは免罪符にならない。
だから書きなおそうかと思うほどの悪文だということは認めてる。わかりやすく書いて悪いことはない。
がんばったねえwでも<関係ない>の省略された主語Sは「この議論」やろね。京大ならわかるが、この程度の悪文も二次英語には出るよ。とはいえ文章が悪いのは認めるよ。投稿した後書きたそうかとちょっと思ったもん。SVOandOをSVOOと書くようなことは絶対ないが、お前が敢えて→みたいなこと言ってしまうことで、お前の周囲はこんな連中がおるくらい底辺なんやろうなってバレてもうたなwww→「調査を依頼をした、みたいなダブル「を」禁止の法則違反しても平気な顔して投稿してそう」
